منابع مشابه
Bacterial transfer RNAs.
Transfer RNA is an essential adapter molecule that is found across all three domains of life. The primary role of transfer RNA resides in its critical involvement in the accurate translation of messenger RNA codons during protein synthesis and, therefore, ultimately in the determination of cellular gene expression. This review aims to bring together the results of intensive investigations into ...
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RNAs have diverse structures that include bulges and internal loops able to form tertiary contacts or serve as ligand binding sites. The recent increase in structural and functional information related to RNAs has put them in the limelight as a drug target for small molecule therapy. In addition, the recognition of the marked difference between prokaryotic and eukaryotic rRNA has led to the dev...
متن کاملSmall RNAs in Bacterial Cell-Cell Communication
M any types of free-living bacteria communicate with one another by chemical signals, thereby coordinating metabolic activities and developmental processes. For instance, starved cells of the myxobacterium Myxococcus xanthus release the A signal, a mixture of six amino acids, to promote aggregation, the first step in the development of a fruiting body. Escherichia coli cells coordinate their mo...
متن کاملEvolutionary variation in bacterial RNase P RNAs.
Sequences encoding RNase P RNAs from representatives of the last remaining classical phyla of Bacteria have been determined, completing a general phylogenetic survey of RNase P RNA sequence and structure. This broad sampling of RNase P RNAs allows some refinement of the secondary structure, and reveals patterns in the evolutionary variation of sequences and secondary structures. Although the se...
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An increasing number of RNAs have been recently shown to possess regulatory functions similar to those of proteins. In bacteria, these regulatory RNAs are usually noncoding and are short size (50–500 nts) transcripts that are often referred to as small RNAs (sRNAs) [1,2]. These sRNAs are synthesized under specific environmental conditions and play a major role in the regulation of various cellu...
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ژورنال
عنوان ژورنال: FEMS Microbiology Reviews
سال: 2015
ISSN: 1574-6976
DOI: 10.1093/femsre/fuv004